| Objective: To retrieve, assess and summarize the best available evidence on standardized physical restraint for adult patients in intensive care unit. Methods: We searched the NICE Guidance, Scottish Intercollegiate Guidelines Network (SIGN), Registered Nurses' Association of Ontario (RNAO), Guidelines International Network (GIN), National Guideline Clearinghouse (NGC), Society of Critical Care Medicine (SCCM), Pubmed, UpToDate, BMJ best practice, Cochrane Library, CNKI, Wanfang Data and OVID. The literature including guidelines, evidence summary, recommended practice and systematic review between 2008-2018 were collected. Results: Eight references were enrolled including two guidelines, one evidence summary and five systematic reviews. Four areas including 23 items of evidence were summarized, including decision-making, implementation, education and management. Conclusion: Healthcare organizations and clinical staff should make relevant policy for implementing physical restraint and carry out standardized intervention to ensure patients' safety as well as decreasing the rate of physical restraint applications.